John Nicholas Selected Research

viral interferon regulatory factors

1/2020	Kaposi's Sarcoma-Associated Herpesvirus Drives a Super-Enhancer-Mediated Survival Gene Expression Program in Primary Effusion Lymphoma.
1/2020	USP7-Dependent Regulation of TRAF Activation and Signaling by a Viral Interferon Regulatory Factor Homologue.
1/2018	Human Herpesvirus 8 Interferon Regulatory Factors 1 and 3 Mediate Replication and Latency Activities via Interactions with USP7 Deubiquitinase.
1/2007	Human herpesvirus 8-encoded proteins with potential roles in virus-associated neoplasia.

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John Nicholas Research Topics

Disease

17	Primary Effusion Lymphoma 01/2021 - 09/2003
11	Kaposi Sarcoma (Kaposi's Sarcoma) 01/2021 - 09/2003
9	Neoplasms (Cancer) 01/2022 - 07/2005
9	Multi-centric Castleman's Disease 01/2021 - 09/2003
3	Infections 01/2020 - 07/2008
2	Virus Diseases (Viral Diseases) 01/2022 - 02/2010
1	Lymphoma (Lymphomas) 01/2020

Drug/Important Bio-Agent (IBA)

9	Interleukin-6 (Interleukin 6)IBA 01/2020 - 01/2007
8	CytokinesIBA 01/2021 - 07/2005
5	Proteins (Proteins, Gene)FDA Link 01/2021 - 01/2007
4	viral interferon regulatory factorsIBA 01/2020 - 01/2007
3	ChemokinesIBA 03/2010 - 01/2007
2	Viral ProteinsIBA 01/2020 - 01/2007
2	Antiviral Agents (Antivirals)IBA 01/2020 - 09/2003
2	Biological ProductsIBA 01/2018 - 01/2007
2	Cytokine Receptor gp130IBA 12/2017 - 10/2013
2	Vitamin K Epoxide ReductasesIBA 08/2015 - 01/2014
2	Cathepsin DIBA 08/2015 - 01/2014
2	Membrane Proteins (Integral Membrane Proteins)IBA 08/2015 - 01/2007
1	TNF-Related Apoptosis-Inducing LigandIBA 01/2022
1	Caspase 8 (Caspase-8)IBA 01/2022
1	MicroRNAs (MicroRNA)IBA 01/2021
1	Deubiquitinating EnzymesIBA 01/2020
1	Transcription Factors (Transcription Factor)IBA 01/2020
1	ChromatinIBA 01/2020
1	TNF Receptor-Associated Factor 3IBA 01/2020
1	TNF Receptor-Associated Factor 6 (TRAF6)IBA 01/2020
1	procathepsin DIBA 01/2019
1	Peptide Hormones (Polypeptide Hormones)IBA 01/2019
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 03/2010
1	CCAAT-Enhancer-Binding Protein-betaIBA 02/2010
1	CC ChemokinesIBA 07/2008
1	DNA (Deoxyribonucleic Acid)IBA 01/2007
1	Chemokine ReceptorsIBA 07/2005
1	LigandsIBA 09/2003

Therapy/Procedure

1	Therapeutics 01/2022